Association between BDNF rs6265 and Obesity in the Boston Puerto Rican Health Study

Table 2

Association between BDNF rs6265 genotype and obesity traits in BPRHS.

BDNF  rs6265	𝑛^a	BMI (kg/m^2)		Waist (cm)		Weight (kg)		Hip (cm)
		Mean ± s.e.^b	𝑃^b	Mean ± s.e.	P	Mean ± s.e.	P	Mean ± s.e.	P
Total
GG	922	31.0±0.3	0.213	101.9±0.6	0.42	81.0±0.7	0.677	107.4±0.6	0.263
GA	313	31.8±0.4		102.3±1.0		81.7±1.1		108.9±0.9
AA	24	30.1±1.5		97.4±3.6		78.5±4.1		107.0±3.3
Total
GG	922	31.0±0.3	0.163	101.9±0.6	0.927	81.0±0.7	0.652	107.4±0.6	0.103
GA + AA	337	31.7±0.4		102.0±1.0		81.5±1.1		108.8±0.9
Women
GG	595	32.3±0.3	0.009	101.1±0.7	0.071	77.4±0.8	0.029	110.3±0.7	0.027
GA + AA	216	33.8±0.5		103.4±1.1		80.6±1.3		113.4±1.1
Men
GG	242	30.0±0.4	0.009	103.7±1.3	0.002	86.2±1.5	0.002	105.8±1.0	0.03
GA + AA	94	28.3±0.6		97.7±1.8		79.5±2.1		102.1±1.4

^an: the sample size, ^bmeans and P values calculated by analysis of covariance using general linear models adjusted for age, smoking status, drinking status, sex, education, Medication use for depression, physical activity and population admixture.