Review Article

Excessive Leucine-mTORC1-Signalling of Cow Milk-Based Infant Formula: The Missing Link to Understand Early Childhood Obesity

Table 1

Leucine content of mammalian milk and growth rate.

SpeciesProtein content of milk (g/100 mL)Leucine content of milk (mg/100 mL)Days (n) for doubling birth weight3

Rat1 8.7 799 4
Cow1 3.4 333 40
Infant formula (HP)2 3.2 308 ?
Infant formula (LP)2 1.6 154 ?
Human milk2 1.2 104 180

1Data according to Davis et al. [37]; 2HP high protein followon infant formula; LP low protein followon infant formula at 6 months of age [39]. 3Data according to Bounous et al. [36].