Research Article

All-Cause Mortality Risk of Metabolically Healthy Obese Individuals in NHANES III

Table 1

Definitions of metabolic health.

HOMA-IRHealthy = <2.5
HOMA-IR (mmol/L ×  μU/mL) = fasting glucose (mmol/L) × fasting insulin (μU/mL)/22.5

ATP-IIIHealthy = ≤2 metabolic syndrome criteria
Fasting glucose ≥5.6 mmol/L (or diabetes medications)
Systolic ≥130 mmHg or diastolic ≥85 mmHg (or antihypertensive medications)
Triglycerides ≥1.7 mmol/L (or cholesterol-lowering medications)
HDL-C <1.04 mmol/L (males), <1.30 mmol/L (females)
Waist circumference >102 cm (males), >88 cm (females)

CombinedHealthy = ≤1 criteria (Karelis et al. [29])
HOMA-IR ≥1.95 (or diabetes medications)
Triglycerides ≥1.7 mmol/L (or cholesterol-lowering medications)
HDL-C <1.04 mmol/L (males), <1.30 mmol/L (females)
LDL-C ≥2.6 mmol/L
Total cholesterol ≥5.2 mmol/L (or cholesterol-lowering medications)

HOMA-IR: homeostasis model assessment-insulin resistance; ATP-III: Adult Treatment Panel-III; BP: blood pressure; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.