Table 4: Anthropometric and clinical characteristics by metabolic health and body mass index category shown as weighted mean (SEM).

DefinitionHealthyUnhealthy
ObeseOverwtLeanObeseOverwtLean

BMI, kg/m2HOMA-IR33.3 (0.3)26.9 (0.1)*22.1 (0.1)*35.1 (0.2)*27.5 (0.1)*23.0 (0.2)*
ATP-III34.1 (0.3)26.9 (0.1)*22.1 (0.1)*35.1 (0.2)27.8 (0.1)*23.2 (0.2)*
Combined34.3 (0.5)26.9 (0.2)*21.8 (0.07)*34.8 (0.2)27.1 (0.08)*22.5 (0.08)*

Waist circumference, cm HOMA-IR104.8 (0.7)92.4 (0.4)*79.4 (0.3)*110.9 (0.5)*95.7 (0.6)*84.5 (0.8)*
ATP-III105.7 (0.8)92.1 (0.3)*79.5 (0.3)*112.2 (0.6)*98.5 (0.6)*86.7 (0.5)*
Combined107.2 (1.5)90.5 (0.8)*77.6 (0.3)*109.8 (0.5)94.4 (0.4)*81.8 (0.4)*

HOMA-IRHOMA-IR1.9 (0.04)1.8 (0.03)1.5 (0.02)*5.7 (0.3)*3.8 (0.09)*3.2 (0.05)*
ATP-III3.2 (0.1)2.2 (0.05)*1.6 (0.03)*6.0 (0.3)*3.5 (0.1)2.5 (0.1)
Combined3.1 (0.3)1.8 (0.06)1.4 (0.03)*5.0 (0.2)*2.6 (0.06)1.8 (0.03)

Glucose, mmol/LHOMA-IR5.2 (0.05)5.2 (0.03)5.0 (0.02)*6.2 (0.1)*5.9 (0.09)*5.8 (0.1)
ATP-III5.3 (0.03)5.2 (0.03)5.1 (0.01)*6.5 (0.1)*6.0 (0.1)*6.0 (0.2)
Combined5.6 (0.3)5.1 (0.04)5.0 (0.02)*6.0 (0.08)5.5 (0.04)5.2 (0.03)

HDL-C, mmol/LHOMA-IR 1.3 (0.04) 1.3 (0.02)1.4 (0.02)*1.1 (0.02)*1.1 (0.02)1.2 (0.03)
ATP-III1.3 (0.02)1.3 (0.02)1.4 (0.02)*1.0 (0.02)*1.0 (0.02)*1.1 (0.05)*
Combined1.4 (0.05)1.4 (0.02)1.5 (0.02)1.1 (0.02)*1.2 (0.02)*1.3 (0.02)§

Triglycerides, mmol/LHOMA-IR1.4 (0.07)1.4 (0.06)1.1 (0.03)*2.2 (0.1)*1.9 (0.08)*1.6 (0.08)
ATP-III1.2 (0.03)1.3 (0.04)1.1 (0.02)2.5 (0.2)*2.3 (0.1)*2.6 (0.2)*
Combined1.0 (0.04)0.9 (0.03)0.8 (0.02)2.1 (0.1)*1.7 (0.05)*1.4 (0.04)*

Total cholesterol, mmol/LHOMA-IR 5.4 (0.1) 5.2 (0.04) 4.9 (0.03) 5.4 (0.05) 5.4 (0.06) 5.2 (0.1)
ATP-III5.1 (0.06)5.1 (0.04)4.9 (0.03)5.6 (0.07)*5.6 (0.08)*5.7 (0.2)
Combined4.2 (0.1)4.2 (0.04)4.3 (0.03)5.5 (0.05)*5.5 (0.04)*5.5 (0.04)*

LDL-Ca, mmol/LHOMA-IR 3.5 (0.1) 3.3 (0.04) 3.0 (0.03)* 3.4 (0.05) 3.4 (0.05) 3.3 (0.1)
ATP-III3.3 (0.06)3.3 (0.03)3.0 (0.03)*3.6 (0.05)3.6 (0.07)3.5 (0.05)
Combined2.3 (0.1)2.4 (0.03)2.4 (0.02)3.5 (0.04)*3.6 (0.03)*3.5 (0.04)*

Systolic BP, mmHgHOMA-IR120.2 (1.4)117.6 (0.6)113.0 (0.4)*124.7 (0.6)121.2 (0.9) 117.6 (1.1)
ATP-III117.0 (0.6)116.8 (0.5)112.8 (0.4)*128.1 (0.8)*125.8 (1.3)*124.5 (1.7)
Combined120.0 (1.4)113.1 (0.7)*111.3 (0.7)*124.0 (0.6)120.3 (0.6)115.3 (0.5)

Diastolic BP, mmHgHOMA-IR 75.8 (1.2) 74.3 (0.5) 70.5 (0.4)* 79.5 (0.5) 77.4 (0.7) 74.3 (1.0)
ATP-III74.2 (0.6)74.0 (0.5)70.4 (0.3)*81.7 (0.6)*80.0 (0.6)*79.1 (1.4)
Combined73.3 (1.8)72.3 (0.7)§69.6 (0.4)79.2 (0.5)76.2 (0.4)72.0 (0.5)

Overwt: overweight; BMI: body mass index; HOMA-IR: homeostasis model assessment-insulin resistance; ATP-III: Adult Treatment Panel III; SEM: standard error of the mean; HDL-C: high density lipoprotein cholesterol; LDL-C: low density lipoprotein cholesterol; BP: blood pressure. All variables measured in the morning after an overnight fast of ≥6 hours, except for LDL-C which was calculated using the Friedewald formula. Data analyzed using SAS survey regression procedure (continuous) or survey frequency procedure (categorical). aLDL missing for participants, * , , , and § significantly different from metabolically healthy obese by the same definition.