Increased Mesohippocampal Dopaminergic Activity and Improved Depression-Like Behaviors in Maternally Separated Rats Following Repeated Fasting/Refeeding Cycles
Figure 4
Tissue contents of dopamine (DA) and dihydroxyphenylacetic acid (DOPAC) in the hippocampus (a), the ventral tegmental area and substantia nigra (b), and the nucleus accumbens (c). After the 21st refeeding session (PND 70), rats were rapidly decapitated, and the tissue contents of DA and DOPAC were analyzed by high-performance liquid chromatography. *P < 0.05 versus MS/FC, NH: nonhandled, MS: maternal separation, FC: free fed control, RFR: repeated fasting/refeeding. Data are presented as means ± S.E.
