Longitudinal Associations of Leisure-Time Physical Activity and Cancer Mortality in the Third National Health and Nutrition Examination Survey (1986–2006)
Table 2
Hazard ratio (HR) (95% CI) for cancer mortality and measures of leisure-time physical activity in NHANES III (1988–2006) participants 20–89 years ().
Whole population
After excluding persons with existing cancer ()
Cancer deaths/number at risk
860/15,535
733/14,951
Any activity
Age-Adjusted
0.92 (0.71–1.19)
1.04 (0.78–1.37)
Adjusted for additional variables1
0.95 (0.72–1.26)
1.10 (0.82–1.48)
Additional adjustment for BMI2
0.97 (0.73–1.29)
1.12 (0.83–1.50)
Regular low-moderate activity
Age-Adjusted
0.89 (0.69–1.17)
1.01 (0.76–1.34)
Adjusted for additional variables1
0.92 (0.69–1.21)
1.07 (0.80–1.43)
Additional adjustment for BMI2
0.93 (0.70–1.24)
1.09 (0.81–1.48)
Regular vigorous activity
Age-adjusted
0.62 (0.37–1.06)
0.73 (0.42–1.26)
Adjusted for additional variables1
0.66 (0.39–1.13)
0.82 (0.48–1.39)
Additional adjustment for BMI2
0.69 (0.40–1.19)
0.85 (0.50–1.44)
Frequency-weighted METS/week3
Age-adjusted
Quartile 1
1.00
1.00
Quartile 2
0.84 (0.67–1.05)
0.92 (0.71–1.18)
Quartile 3
0.72 (0.54–0.96)
0.80 (0.59–1.08)
Quartile 4
0.86 (0.68–1.10)
0.97 (0.78–1.26)
value4
0.120
0.353
Adjusted for additional variables1
Quartile 1
1.00
1.00
Quartile 2
0.85 (0.67–1.08)
0.95 (0.73–1.23)
Quartile 3
0.74 (0.56–0.98)
0.85 (0.64–1.14)
Quartile 4
0.89 (0.68–1.16)
1.04 (0.79–1.36)
value4
0.139
0.422
Additional adjustment for BMI2
Quartile 1
1.00
1.00
Quartile 2
0.85 (0.67–1.09)
0.95 (0.73–1.24)
Quartile 3
0.75 (0.57–1.00)
0.87 (0.65–1.15)
Quartile 4
0.91 (0.69–1.30)
1.06 (0.79–1.41)
value4
0.132
0.426
1Adjusted for age, race, sex, and smoking. 2Adjusted for age, race, sex, smoking, and BMI. 3Quartile cutoffs (METS/week) quartile 1 <1.16; quartile 2: 1.16–10.47; quartile 3: 10.48–32; quartile 4: >48.33. 4 value for difference between quartiles.
