Leptin Deficiency and Its Effects on Tibial and Vertebral Bone Mechanical Properties in Mature Genetically Lean and Obese JCR:LA-Corpulent Rats

Table 2

Tibial structural properties.

	Lean	Obese	𝑛
Flexural rigidity (N·mm^2·10^3)	5.37 ± 0.81	5.40 ± 0.34	5868
Load at proportional limit (N)	25.49 ± 2.94^*	30.22 ± 3.41
Displacement at proportional limit (mm)	0.26 ± 0.04^*	0.30 ± 0.02
Maximal load (N)	36.13 ± 4.48	39.34 ± 3.67	26
Displacement at maximal load (mm)	0.61 ± 0.10	0.60 ± 0.08	1272
Energy to proportional limit (N·mm·10^3)	4.12 ± 0.76	5.06 ± 0.89	49
Energy to maximal load (N·mm·10^4)	1.78 ± 0.45	1.56 ± 0.78	123

Values are means ± SD. ^*denotes statistically significant (𝑃≤0.05). 𝑛 denotes the sample size per group needed for the recorded differences to become statistically significant based on a power of 0.8.