Influence of Weight Loss, Body Composition, and Lifestyle Behaviors on Plasma Adipokines: A Randomized Weight Loss Trial in Older Men and Women with Symptomatic Knee Osteoarthritis
Table 2
Measures of body weight and body composition outcomes and diet and physical activity behaviors at baseline and 6 month followup separated by gender. Statistical analysis was performed on 6 month values.
Variable
Weight stable
Weight loss
95% confidence interval {cutoff for 50% power} for mean difference (WL − WS) at 6 Month
Men
Women
Men
Women
Men
Women
()
()
()
()
Weight, kg
Baseline
110.3 (5.3)
94.6 (3.8)
121.3 (2.8)
90.7 (3.6)
6 months
111.4 (2.7)
92.9 (1.4)
101.3 (3.0)
87.2 (1.3)
(−18.9, −1.4)*
(−9.8, −1.6)*
{±8.8}
{±4.1}
Weight change (%)
−1.0 (2.1)
0.6 (1.6)
−13.0 (2.3)
−6.7 (1.6)
(−18.7, −5.3)*
(−12.1, −2.4)*
{±6.7}
{±4.9}
Body mass index, kg/m2
Baseline
34.4 (1.7)
35.6 (1.2)
38.5 (1.8)
34.2 (1.2)
6 months
35.0 (0.9)
35.0 (0.6)
32.1 (1.0)
32.8 (0.5)
(−6.0, 0.2)
(−3.8, −0.5)*
{±3.1}
{±1.7}
Body fat, kg
Baseline
38.8 (2.2)
42.8 (2.4)
38.9 (2.4)
42.6 (2.4)
6 months
38.9 (1.7)
44.3 (1.6)
34.3 (1.9)
37.5 (1.5)
(−9.9, 0.7)
(−11.4, −2.2)*
{±5.3}
{±4.6}
Body fat (%)
Baseline
34.6 (1.3)
45.7 (1.0)
34.1 (1.5)
45.5 (0.9)
6 months
34.0 (1.0)
45.7 (0.6)
32.1 (1.1)
42.6 (0.6)
(−5.2, 1.4)
(−4.9, −1.2)*
{±3.3}
{±1.9}
Trunk fat, kg
Baseline
20.7 (1.3)
20.5 (1.1)
23.4 (1.5)
19.7 (1.0)
6 months
21.3 (1.2)
20.2 (0.6)
18.8 (1.4)
17.8 (0.6)
(−6.8, 1.6)
(−4.2, −0.7)*
{±4.2}
{±1.8}
Fat free mass, kg
Baseline
73.0 (2.5)
52.1 (1.7)
70.4 (2.8)
49.5 (1.6)
6 months
74.3 (0.9)
51.1 (0.6)
69.7 (1.1)
50.0 (0.6)
(−7.7, −1.4)*
(−2.9, 0.6)
{±3.2}
{±1.8}
Step counts,
Baseline
4720 (649)
5065 (790)
3339 (723)
3555 (727)
6 months
4719 (715)
4676 (1030)
7698 (801)
7101 (769)
(535, 5421)*
(−555, 5405)
{±2443}
{±2980}
Energy intake, kcals
Baseline
2050.4 (168)
1881 (150)
1917 (197)
1561 (139)
6 months
2088 (120)
1641 (125)
1489 (141)
1431 (115)
(−1012, −186)*
(−584, 164)
{±413}
{±374}
Fat intake, % kcals
Baseline
35.7 (2.0)
38.4 (2.2)
33.7 (2.4)
35.4 (2.0)
6 Months
36.9 (2.5)
35.6 (1.3)
34.6 (2.9)
27.7 (1.2)
(−20.9, −3.7)*
(−11.6, −4.2)*
{±8.6}
{±3.7}
Carbohydrate intake, % kcals
Baseline
48.8 (2.7)
48.0 (2.6)
47.3 (3.2)
50.8 (2.4)
6 months
47.3 (2.9)
50.1 (2.0)
59.5 (3.4)
57.6 (1.8)
(2.4, 22.0)*
(1.7, 13.3)*
{±9.8}
{±5.8}
Protein intake, % kcals
Baseline
15.0 (1.1)
15.7 (0.7)
18.1 (1.3)
16.2 (0.7)
6 months
15.4 (1.0)
16.6 (1.1)
18.6 (1.2)
18.4 (1.0)
(−0.4, 6.8)
(−1.3, 5.0)
{±3.6}
{±3.2}
Values are estimated marginal mean (SEM).
*Indicates for comparison between (WL versus WS) groups within gender. Indicates to for comparison between groups within gender. The power is 50% if the absolute value of the true mean difference equals the half width of the respective 95% confidence interval.
