About this Journal Submit a Manuscript Table of Contents
Journal of Obesity
Volume 2012 (2012), Article ID 730409, 15 pages
http://dx.doi.org/10.1155/2012/730409
Clinical Study

Influence of Running and Walking on Hormonal Regulators of Appetite in Women

1Department of Family and Consumer Sciences, University of Wyoming, Laramie, WY 82071, USA
2Department of Biostatistics, University of Washington, Seattle, WA 98195, USA
3Department of Animal Science, University of Wyoming, Laramie, WY 82071, USA
4Fay W. Whitney School of Nursing, University of Wyoming, Laramie, WY 82071, USA

Received 14 October 2011; Accepted 22 December 2011

Academic Editor: Pietro Forestieri

Copyright © 2012 D. Enette Larson-Meyer et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Nine female runners and ten walkers completed a 60 min moderate-intensity (70% VO2max) run or walk, or 60 min rest in counterbalanced order. Plasma concentrations of the orexogenic peptide ghrelin, anorexogenic peptides peptide YY (PYY), glucagon-like peptide-1 (GLP-1), and appetite ratings were measured at 30 min interval for 120 min, followed by a free-choice meal. Both orexogenic and anorexogenic peptides were elevated after running, but no changes were observed after walking. Relative energy intake (adjusted for cost of exercise/rest) was negative in the meal following running (194±206 kcal) versus walking (41±196 kcal) (P=0.015), although both were suppressed (P<0.05) compared to rest (299±308 and 284±121 kcal, resp.). The average rate of change in PYY and GLP-1 over time predicted appetite in runners, but only the change in GLP-1 predicted hunger (P=0.05) in walkers. Results provide evidence that exercise-induced alterations in appetite are likely driven by complex changes in appetite-regulating hormones rather than change in a single gut peptide.