Adult BMI Change and Risk of Colon Cancer in Postmenopausal Women

Table 1

Characteristics of the Kentucky colon cancer genetic epidemiology study postmenopausal females.

Characteristic	Cases (𝑁=516)	Controls (𝑁=941)	𝑃 value^a
Age (years)	63.8 (8.9)^b	63.4 (9.4)^b	0.38
Race
Caucasian	483 (93.6%)	878 (93.3%)	0.43
African American	24 (4.7%)	54 (5.7%)	—
Other	8 (1.6%)	7 (0.7%)	—
Unknown	1 (0.2%)	2 (0.2%)
Education
<8 years	16 (3.1%)	8 (0.9%)	<0.001
8–11 years	62 (12.0%)	78 (8.3%)	—
High school; (HS) diploma	165 (32.0%)	260 (27.6%)	—
Some post-HS training	165 (32.0%)	318 (33.8%)	—
Bachelor’s degree	43 (8.3%)	114 (12.1%)	—
Graduate degree	65 (12.6%)	163 (17.3%)	—
Income
<$15,000	89 (17.2%)	118 (12.5%)	<0.001
$15,000–$29,000	122 (23.6%)	174 (18.5%)	—
$30,000–$44,000	93 (18.0%)	182 (19.3%)	—
$45,000–$69,000	96 (18.6%)	164 (17.4%)	—
≥$70,000	83 (16.1%)	229 (24.3%)	—
Refused	33 (6.4%)	74 (7.8%)	—
Cigarette smoker
Ever	244 (47.2%)	460 (48.9%)	0.04
Never	262 (50.8%)	476 (50.6%)
Unknown	10 (1.9%)	5 (0.5%)
Alcohol drinker
Yes	147 (28.5%)	353 (37.5%)	<0.001
No	354 (68.6%)	550 (58.4%)
Unknown	15 (2.9%)	38 (4.0%)
Family history of colorectal cancer
Yes	192 (37.2%)	276 (29.3%)	0.004
No	295 (57.2%)	588 (62.5%)
Unknown	29 (5.6%)	77 (8.2%)
NSAIDs use
Yes	189 (36.6%)	420 (44.6%)	0.003
No	327 (63.4%)	521 (55.4%)
HRT
Yes	222 (43.0%)	573 (60.9%)	<0.001
No	290 (56.2%)	356 (37.8%)
Unknown	4 (0.8%)	12 (1.3%)
Physical activity
20s  Light intensity^c	76 (14.7%)	133 (14.1%)	0.80
Moderate intensity^c	391 (75.8%)	709 (75.3%)	—
Vigorous intensity^c	49 (9.5%)	99 (10.5%)	—
30s  Light intensity^c	72 (14.0%)	120 (12.8%)	0.20
Moderate intensity^c	411 (79.7%)	737 (78.3%)	—
Vigorous intensity^c	33 (6.4%)	84 (8.9%)	—
50s  Light intensity^c	96 (18.6%)	208 (22.1%)	0.19
Moderate intensity^c	398 (77.1%)	685 (72.8%)	—
Vigorous intensity^c	22 (4.3%)	48 (5.1%)	—

^a𝑃 value for 𝑡-test or 𝜒²-test with 𝑘 (number of groups)—1 degrees of freedom. ^bMean and SD of the mean in parentheses. ^cLight intensity: 1 to <3.0 metabolic equivalents (METs); moderate intensity: ≥3.0 to ≤6.0 METs; vigorous intensity: >6.0 METs.