Research Article

The Epidemiological Boehringer Ingelheim Employee Study—Part I: Impact of Overweight and Obesity on Cardiometabolic Risk

Table 3

Prevalence of cardiometabolic diseases.

ParameterPrevalence
All participants
( ) [95% CI]
Stratified by sex (male/female)Stratified by age (<50/≥50 years)

Hypertension [%]141 [39–43]49/28 *** 33/58 ***
Hypertriglyceridemia [%]223 [21–24]30/13 *** 20/28 ***
Hypercholesterolemia [%]362 [60–64]65/58 *** 58/74 ***
Metabolic syndrome [%]424 [22–26]35/9 *** 19/37 ***
Hyperinsulinemia [%]512 [11–13]15/8 *** 9/18 ***
Insulin resistance [%]623 [21–25]28/17 *** 19/33 ***
Type 2 diabetes mellitus [%]74 [3–5]5/43/7 ***
Increased IMT [%]82 2-3 4/1 *** 1/6 ***
Arteriosclerosis [%]916 [15–18]19/12 *** 9/33 ***
Cardiovascular disease [%]106 [5–7]6/65/8 **

Systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg or self-reported; 2triglycerides ≥ 150 mg/dL; 3total cholesterol ≥ 200 mg/dL or self-reported; 4waist circumference ≥ 94 cm in men, ≥80 cm in women, and two of the following criteria: hypertriglyceridemia; HDL cholesterol < 50 mg/dL in men, <40 mg/dL in women; systolic blood pressure ≥ 135 mmHg and/or diastolic blood pressure ≥ 85 mmHg; fasting glucose ≥ 100 mg/dL; 5fasting insulin > 15 μU/mL; 6HOMA index ≥ 2.6; 7fasting glucose ≥ 126 mg/dL and/or HbA1c ≥ 6.5% and/or self-report of type 2 diabetes mellitus; 8intima media thickness (IMT) > 1 mm; 9plaques in abdominal arteries (aorta abdominalis) and/or plaques in neck arteries (aorta carotis) and/or stenoses in neck arteries (aorta carotis); 10Angina pectoris and/or coronary stenoses and/or myocardial infarction and/or cardiac arrhythmia and/or heart failure and/or stroke or TIA. There were 244–443 missings in the variables hypertension, metabolic syndrome, insulin resistance, increased IMT, and arteriosclerosis. In the other variables there were 7–74 missings. Differences had been determined by Chi-square test (** ; *** ). Significant differences were bold written.