296537.fig.001a
(a)
296537.fig.001b
(b)
296537.fig.001c
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296537.fig.001d
(d)
Figure 1: Increased body weight and reduced insulin sensitivity are characteristics of leptin deficient Ob/Ob mice. Body weight (a), fasting blood glucose (b), fasting plasma insulin (c), and homeostasis model assessment (HOMA) (d) were elevated in 14-week-old male Ob/Ob mice as compared to age-matched male wild-type (WT) mice. Values are means SE ( ); * .