Research Article

Altered Hepatic Lipid Metabolism Contributes to Nonalcoholic Fatty Liver Disease in Leptin-Deficient Ob/Ob Mice

Figure 2

Ob/Ob mice display hepatic lipid accumulation and increased hepatic inflammation. Representative H&E stained images from the livers of age-matched wild-type (WT) (a) and Ob/Ob (b) mice fed a standard rodent chow. Triglyceride content (c) and relative gene expression of inflammatory factors (d) were significantly increased in the livers of Ob/Ob mice. Values are means SE ( ); * .
296537.fig.002a
(a)
296537.fig.002b
(b)
296537.fig.002c
(c)
296537.fig.002d
(d)