Table 5: Change in values for cardiovascular disease risk factors within the ILI-group. Data are mean values (SD or 95% CI).

Mean
Week 0
Mean change
Week 0 to 12 months
P valueMean change
Week 0 to weeks 10–14
P valueMean change
Weeks 10–14 to six months
P valueMean change
Six to 12 months
P value

s-BP (mmHg)
 All ( )132.3 (10.7)−2.8 (−6.0, 0.4)0.082a−6.4 (−9.1, −3.7)<0.0001a1.1 (−1.7, 4.0)0.431a2.5 (−0.5, 5.4)0.097a
 No blood pressure lowering ( )130.4 (8.8)−3.8 (−6.9, −0.7)0.018b−5.4 (−8.4, −2.4)0.001b0.3 (−3.2, 3.8)0.877b1.4 (−1.7, 4.4)0.368b
d-BT (mmHg)
 All ( )83.7 (6.1)−1.8 (−4.0, 0.3)0.094a−1.3 (−3.2, 0.6)0.175a−2.0 (−4.3, 0.3)0.088a1.5 (−0.7, 3.7)0.173a
 No blood pressure lowering ( )83.2 (5.4)−3.5 (−6.3, −0.7)0.015b−2.8 (−5.0, −0.7)0.012b−2.3 (−5.2, 0.6)0.112b1.6 (−1.2, 4.4)0.245b
GLUC (mmol/L)
 All ( )5.8 (1.3)−0.5 (−0.7, −0.3)<0.0001a−0.7 (−0.9, −0.5)<0.0001a0.1 (−0.1, 0.2)0.258a0.1 (0.0, 0.3)0.150a
 No glucose lowering ( )5.6 (0.8)−0.4 (−0.6, −0.2)<0.0001b−0.6 (−0.8, −0.4)<0.0001b0.1 (−0.1, 0.2)0.260b0.1 (−0.1, 0.2)0.300b
HDL (mmol/L)
 All ( )1.1 (0.3)0.3 (0.3, 0.4)<0.0001a0.1 (0.0, 0.1)0.001a0.2 (0.1, 0.2)<0.0001a0.1 (0.0, 0.2)0.001a
 No lipid lowering ( )1.1 (0.3)0.3 (0.3, 0.4)<0.0001b0.1 (0.0, 0.1)0.002b0.2 (0.1, 0.2)<0.0001b0.1 (0.0, 0.2)0.004b
LDL (mmol/L)
 All ( )2.9 (0.9)0.4 (0.2, 0.6)<0.0001a−0.2 (−0.3, −0.1)0.005a0.3 (0.2, 0.4)<0.0001a0.3 (0.2, 0.4)<0.0001a
 No lipid lowering ( )3.1 (0.8)0.3 (0.1, 0.5)0.002b−0.3 (−0.4, −0.1)<0.0001b0.2 (0.1, 0.3)<0.0001b0.3 (0.2, 0.5)<0.0001b
TG (mmol/L)
 All ( )1.4 (0.6)−0.1 (−0.2, 0.1)0.231a−0.2 (−0.3, −0.2)<0.0001a0.0 (0.0, 0.2)0.066a0.1 (−0.1, 0.2)0.420a
 No lipid lowering ( )1.4 (0.6)−0.1 (−0.3, 0.1)0.185b−0.2 (−0.3, −0.2)<0.0001b0.0 (−0.1, 0.1)0.451b0.1 (0.0, 0.3)0.126b
Tot C (mmol/L)
 All ( )4.7 (1.1)0.5 (0.3, 0.7)<0.0001a−0.1 (−0.3, 0.0)0.155a0.4 (0.2, 0.5)<0.0001a0.3 (0.1, 0.4)0.002a
 No lipid lowering ( )4.9 (1.0)0.4 (0.2, 0.6)<0.0001b−0.2 (−0.3, 0.0)0.015b0.3 (0.2, 0.5)<0.0001b0.3 (0.1, 0.5)0.002b
Waist circumferences (cm)
 All ( )123.5 (12.8)−14.9 (−16.9, −13.0)<0.0001a−14.0 (−14.9, −13.0)<0.0001a−4.6 (−5.6, −3.5)<0.0001a3.6 (2.5, 4.7)<0.0001a

s-BP: blood pressure systolic, d-BP: blood pressure diastolic, GLUC: fasting glucose, HDL: high-density lipoprotein cholesterol, LDL: low-density lipoprotein cholesterol, TG: triglycerides, Tot C: total cholesterol. aGLM adjusted for age, gender, and relevant medication at baseline (HDL, LDL, Tot C, and TG adjusted for lipid-lowering medication at baseline; s-BP and d-BP adjusted for blood pressure-lowering medication at baseline; and GLUC adjusted for glucose-lowering medication at baseline), bsubgroup analysis of participants not using relevant medication at baseline, GLM adjusted for age and gender.