Table 1: Clinical characteristics, lipids and inflammatory markers in subjects with type 2 diabetes, and normal glucose tolerance before (pre) and 1 wk, 3 mo, and 1 yr after Roux-en-Y gastric bypass.

Pre1 wk3 mo1 yr    valueII

(% of total)T2D10 (50)9 (47)10 (53)10 (50)
NGT10 (50)10 (53)9 (47)10 (50)

Systolic BP,
mmHg*
T2D136 (15)131 (13)134 (10)138 (12)0.5170.295
NGT135 (6)136 (12)136 (12)130 (14)0.411
value0.8760.4320.7880.214

Diastolic BP,
mmHg*
T2D83 (7)79 (8)81 (7)83 (9)0.5120.117
NGT81 (11)75 (9)78 (6)73 (9)0.010
value0.5980.3130.3830.036

Weight,
Kg*
T2D125.9 (14.4)124.5 (13.9)109.0 (15.6)96.9 (20.6)<0.00010.578
NGT130.3 (10.4)127.2 (9.6)108.8 (7.6)98.0 (12.1)<0.0001
value0.4410.6280.9720.886

BMI,
Kg/m2*
T2D42.5 (5.7)41.9 (6.0)36.8 (6.1)32.8 (8.2)<0.00010.738
NGT42.5 (4.6)41.4 (4.2)35.2 (2.9)32.1 (4.4)<0.0001
value0.9770.8300.4830.797

WHR*T2D1.0 (0.1)1.1 (0.1)1.1 (0.1)1.0 (0.1)0.0300.589
NGT1.1 (0.1)1.1 (0.1)1.0 (0.1)1.0 (0.1)0.017
value0.9170.6500.6470.832

TG,
mmol/L*
T2D1.51 (0.36)1.58 (0.22)1.38 (0.45)1.10 (0.39)0.0170.385
NGT1.35 (0.46)1.61 (0.53)1.17 (0.44)0.98 (0.41)0.005
value0.4000.8670.3110.512

FFA,
mmol/L*
T2D0.80 (0.25)0.92 (0.22)0.74 (0.20)0.54 (0.12)<0.00010.859
NGT0.73 (0.30)0.78 (0.19)0.70 (0.26)0.50 (0.28)0.087
value0.5870.1620.7100.690

YKL-40,
µg/L
T2D51 (37; 88)47 (35; 71)62 (49; 110)59 (35; 94)0.1200.362
NGT43 (22; 99)61 (31; 76)44 (31; 88)51 (27; 97)0.930
value0.3880.9470.1560.449

MCP-1,
pg/mL
T2D25.2 (11.3; 35.5)20.4 (9.0; 24.4)15.9 (8.6; 19.9)9.7 (6.4; 11.9)<0.00010.213
NGT14.9 (12.4; 42.1)17.8 (13.7; 34.4)13.1 (9.2; 22.9)11.1 (6.6; 16.1)<0.0001
value0.9200.5330.8870.333

Data are presented as *mean (SD), median (IQR), or number (%) where not specified.
value for comparison of T2D and NGT; Independent Samples -test.
-value for overall comparison between days within a group (T2D or NGT); repeated measures.
value for overall comparison of changes between the groups (T2D and NGT); repeated measures.
BMI: body mass index; DBP: diastolic blood pressure; FFA: free fatty acids; MCP-1: monocyte chemoattractant protein-1; NGT: normal glucose tolerance; SBP: systolic blood pressure; T2D: type 2 diabetes; TG: triglyceride; WHR: waist-hip ratio.