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Journal of Obesity
Volume 2013 (2013), Article ID 454285, 9 pages
http://dx.doi.org/10.1155/2013/454285
Clinical Study

Waist Circumference as Measure of Abdominal Fat Compartments

1Departments of Internal Medicine, Clinical Nutrition and Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, TX, USA
2Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX, USA

Received 13 February 2013; Accepted 1 April 2013

Academic Editor: Anne E. Sumner

Copyright © 2013 Scott M. Grundy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This study examines intercorrelations among waist circumference (WC), intraperitoneal fat (IPF), and subcutaneous abdominal fat (SAF) in ethnically diverse Dallas Heart Study consisting of 1538 women and 1212 men (50% Black). Correlations between fat depots and triglyceride or HOMA2-IR, biomarkers of metabolic syndrome, are also reported. Total abdominal fat (TAF), ASF, and IPF masses were measured by magnetic resonance imaging. The highest correlations with WC according to ethnicity and gender were noted for TAF with progressively lower correlations with ASF (0.65–0.82) and IPF (0.29–0.85). The percentage of IPF relative to TAF was not significantly correlated with WC. For all WC categories, higher IPF/ASF ratios were associated with higher triglyceride levels. In contrast, differences in ratios had little or no association with HOMA2-IR. However, when all data were pooled, IPF was positively correlated with both triglyceride ( (men) and 0.363 (women)) and HOMA2-IR ( (men) and 0.517 (women)); after adjustment for ASF, IPF was still correlated with triglyceride ( (men) and 0.348 (women)) and HOMA2-IR ( (men) and 0.221 (women)). WC measures TAF reliably, but its association with IPF depends on IPF/ASF ratios that vary by gender and ethnicity.