Table 3: Correlations of gene methylation and expression with CRP levels for genes from the IL-8 signaling pathway.

Gene symbol Methylation probe1LocalizationTranscript accession number Gene methylation versus expression ( ) Gene methylation versus hsCRP level ( ) Gene expression versus hsCRP level ( )
Pearson valuePearson valuePearson value

BCL2cg08223235Gene bodyNM_000633 0.002 <0.0001 0.02
CCND2cg27317813Gene bodyNM_001759 <0.0001 <0.0001 0.02
CXCR1cg130489675′UTRNM_000634 0.003 0.001 0.17
CXCR1cg157681385′UTRNM_000634 0.002 0.0004 0.17
GNA12cg01139696Gene bodyNM_007353 0.02 0.32 0.33
GNA12cg06544239Gene bodyNM_007353 0.004 0.32 0.33
GNA13cg25554496Gene bodyNM_006572 0.01 0.0002 0.08
GNAI3cg19244300Gene bodyNM_006496 0.04 0.0002 0.35
GNB2L1cg01919999Gene bodyNM_006098 0.003 0.002 0.25
GNG2cg270197175′UTRNM_053064 0.004 <0.0001 0.12
GNG7cg046031305′UTRNM_052847 0.007 <0.0001 0.10
GNG7cg243397045′UTRNM_052847 0.007 <0.0001 0.10
GNG7cg269881385′UTRNM_052847 0.05 0.008 0.10
ITGAXcg04742550TSS200NM_000887 0.03 0.01 0.38
LIMK2cg077139463′UTRNM_016733 0.03 0.001 0.06
MAP4K4cg13522882Gene bodyNM_145687 0.04 0.0004 0.29
NCF2cg090761235′UTRNM_000433 0.04 0.0002 0.03
NCF2cg09472600Gene bodyNM_000433 0.007 <0.0001 0.03
PIK3C2Bcg211953765′UTRNM_002646 0.05 0.0004 0.28
PIK3R1cg00067720TSS1500NM_181523 0.0008 <0.0001 0.01
PRKCAcg14648237Gene bodyNM_002737 0.003 0.0001 0.06
PRKCAcg22435313Gene bodyNM_002737 0.01 <0.0001 0.06
PRKCHcg14001486Gene bodyNM_006255 <0.0001 <0.0001 0.04

Bold: significantly correlate in all 3 analyses.