Table 3: Odds ratios from logistic regression models predicting high levels of C-reactive protein and White blood cell count by 1- and 10-year change in weight categorizes.

High C-reactive protein*High White blood cell count*
Model IModel IIModel IModel II
OR(95% CI)OR(95% CI)OR(95% CI)OR(95% CI)

Weight change in past 1 year
 Loss
  ≥10 kg1.67(1.08–2.60)1.61(1.032.50)1.25(0.81–1.93)1.13(0.73–1.75)
  4–9 kg0.98(0.70–1.37)0.92(0.70–1.38)1.21(0.89–1.64)1.22(0.89–1.67)
 Stable (<4 kg)ReferenceReferenceReferenceReference
 Gain
  4–9 kg1.28(0.70–1.37)1.30(0.92–1.83)1.22(0.89–1.68)1.27(0.91–1.77)
  ≥10 kg1.94(1.10–3.43)1.96(1.10–3.50)0.97(0.54–1.74)0.97(0.55–1.73)

Weight change in past 10 years
 Loss
  ≥10 kg1.24(0.78–1.99)1.24(0.77–2.00)1.21(0.78–1.86)1.19(0.77–1.84)
  4–9 kg1.26(0.83–1.90)1.23(0.82–1.86)1.29(0.88–1.90)1.21(0.82–1.78)
 Stable (<4 kg)ReferenceReferenceReferenceReference
 Gain
  4–9 kg1.24(0.91–1.69)1.27(0.93–1.73)1.01(0.75–1.36)1.06(0.78–1.42)
  ≥10 kg1.62(1.162.27)1.62(1.162.26)0.96(0.69–1.33)0.92(0.66–1.29)

*High levels included individuals in the highest sample-based quartile (CRP > 0.51 mg/dL; WBC > cells/ L).
Model I adjusts for age, sex, and current BMI.
Model II adjusts for current smoking status and total cholesterol in addition to Model I covariates.
OR: odds ratio; CI: confidence interval.
Bold indicates significant at the .05 level.