Journal of Obesity

Clinical Study

The Impact of Rapid Weight Loss on Oxidative Stress Markers and the Expression of the Metabolic Syndrome in Obese Individuals

Table 1

Baseline characteristics among 20 lean controls and 80 obese adults with and without the metabolic syndrome (values are expressed as ^amedian (IQR), all others as means ± SE).


Characteristics	Lean	Obese		value (3 groups)	value (pairwise)
Characteristics	Controls ()	MS− ()	MS+ ()	value (3 groups)	LC versus MS−	LC versus MS+	MS− versus MS+

Age (years)				0.2823^b	0.280^c	0.113^c	0.527^c
Gender (% female)	60	83	58	0.0388^b	0.076^c	0.842^c	0.016^c
Weight (kg)				<0.0001^b	<0.001^c	<0.001^c	0.006^c
BMI (kg/m²)				<0.0001^b	<0.001^c	<0.001^c	0.444^c
Waist (in)				<0.0001^b	<0.001^c	<0.001^c	0.003^c
SBP (mmHg)				<0.0001^b	0.080^c	<0.001^c	<0.001^c
DBP (mmHg)				<0.0001^b	<0.001^c	<0.001^c	0.005^c
Glucose^a (mg/dL)	87.0 (81.5, 93.0)	94.0 (87.0, 99.0)	97.5 (88.5, 107.5)	0.0025	0.032	0.001	0.058
Insulin^a (mU/L)	4.53 (3.63, 7.42)	12.57 (6.85, 16.91)	17.44 (11.04, 27.69)	0.0001	<0.001	<0.001	0.004
HOMA-IR^a	0.95 (0.82, 1.58)	2.66 (1.62, 4.14)	4.23 (2.63, 11.29)	0.0001	<0.001	<0.001	0.002
Triglycerides^a (mg/dL)	90.5 (66.5, 127.5)	110.5 (91.5, 133.0)	225.5 (176.0, 292.5)	0.0001	0.086	<0.001	<0.001
HDL (mg/dL)				<0.0001^b	0.853^c	<0.001^c	<0.001^c
LDL (mg/dL)				0.7409^b	0.459^c	0.749^c	0.620^c
Total cholesterol (mg/dL)				0.6120^b	0.658^c	0.340^c	0.530^c
ox-LDL (U/L)				0.0011^b	0.153^c	<0.001^c	0.011^c
MPO^a (pM)	163.1 (84.4, 259.7)	250.1 (181.7, 392.8)	240.3 (164.3, 393.2)	0.0253	0.015	0.013	0.927
Lp-PLA₂ activity (nmol/mL/min)				0.2600^b	0.764^c	0.307^c	0.113^c
MS factor^a	0.00 (0.00, 1.00)	1.00 (1.00, 2.00)	3.00 (3.00, 4.00)	0.0001	<0.001	<0.001	<0.001

values calculated using ^athe Kruskal-Wallis test, ^bone-way ANOVA, and ^cpost-ANOVA pairwise comparison of means.