Table 1: Baseline characteristics among 20 lean controls and 80 obese adults with and without the metabolic syndrome (values are expressed as amedian (IQR), all others as means ± SE).

CharacteristicsLeanObese value
(3 groups)
value (pairwise)
Controls ( )MS− ( )MS+ ( )LC versus MS−LC versus MS+MS− versus MS+

Age (years) 0.2823b0.280c0.113c0.527c
Gender (% female)6083580.0388b0.076c0.842c0.016c
Weight (kg) <0.0001b<0.001c<0.001c0.006c
BMI (kg/m2) <0.0001b<0.001c<0.001c0.444c
Waist (in) <0.0001b<0.001c<0.001c0.003c
SBP (mmHg) <0.0001b0.080c<0.001c<0.001c
DBP (mmHg) <0.0001b<0.001c<0.001c0.005c
Glucosea (mg/dL)87.0 (81.5, 93.0)94.0 (87.0, 99.0)97.5 (88.5, 107.5)0.00250.0320.0010.058
Insulina (mU/L)4.53 (3.63, 7.42)12.57 (6.85, 16.91)17.44 (11.04, 27.69)0.0001<0.001<0.0010.004
HOMA-IRa0.95 (0.82, 1.58)2.66 (1.62, 4.14)4.23 (2.63, 11.29)0.0001<0.001<0.0010.002
Triglyceridesa (mg/dL)90.5 (66.5, 127.5)110.5 (91.5, 133.0)225.5 (176.0, 292.5)0.00010.086<0.001<0.001
HDL (mg/dL) <0.0001b0.853c<0.001c<0.001c
LDL (mg/dL) 0.7409b0.459c0.749c0.620c
Total cholesterol (mg/dL) 0.6120b0.658c0.340c0.530c
ox-LDL (U/L) 0.0011b0.153c<0.001c0.011c
MPOa (pM)163.1 (84.4, 259.7)250.1 (181.7, 392.8)240.3 (164.3, 393.2)0.02530.0150.0130.927
Lp-PLA2 activity (nmol/mL/min) 0.2600b0.764c0.307c0.113c
MS factora0.00 (0.00, 1.00)1.00 (1.00, 2.00)3.00 (3.00, 4.00)0.0001<0.001<0.001<0.001

values calculated using athe Kruskal-Wallis test, bone-way ANOVA, and cpost-ANOVA pairwise comparison of means.