Review Article

The Role of Adipose Tissue in Insulin Resistance in Women of African Ancestry

Table 1

Ethnic differences in adipose tissue lipolysis.

ParticipantsSystemEthnic differences in lipolysisReferences

Nondiabetic, premenopausal, obese black and white US womenIn vivo Black < white for basal and insulin-suppressed systemic glycerol turnover, but not FFA turnoverAlbu et al. [43]
Premenopausal, centrally obese black and white US womenIn vivo Black < white for basal and epinephrine-stimulated lipolysisRacette et al. [44]
Morbidly obese black and white US womenIn vitro Black < white for basal lipolysis in VAT and SAT;
black = white for isoproterenol-stimulated lipolysis, with and without insulin, in VAT and SAT
Barakat et al. [45]
Postmenopausal, overweight black and white US womenIn vitro Black > white for basal and insulin-inhibited lipolysis of abdominal SATFried et al. [46]
Premenopausal, obese black and white South African (SA) womenIn vivo Black > white for basal and insulin-inhibited lipolysis of abdominal SATVan Der Merwe et al. [6]
Premenopausal, obese black and white SA womenIn vitro Black > white for insulin-inhibited lipolysis of abdominal SATButhelezi et al. [47]
Premenopausal, normal-weight and obese black and white SA womenIn vivo Black = white for basal and insulin-suppressed lipolysisGoedecke et al. [48]