Table 1: Demographic and cardiometabolic characteristics* of metabolically healthy obese (MHO)+ and metabolically unhealthy obese (MUO) phenotypes in adolescents and adults.

Adolescents 12–18 years ( )Adults 19–44 years ( )Adults 45–85 years ( )
MHOMUOP valueMHOMUOP valueMHOMUOP value

(% of age group)163 (68)62 (32)152 (54)118 (45)64 (24)207 (76)

Demographic and cardiometabolic variables
 Age (yrs) 0.32 <0.0001 0.26
 Male (%)67 (42)40 (69)0.00663 (43)66 (59)0.0538 (64)100 (46)0.11
 Ethnicity (%)
  Non-Hispanic white35 (58)19 (67)0.1550 (57)48 (67)0.2236 (79)126 (84)0.61
  Non-Hispanic black66 (20)11 (7)55 (21)33 (14)15 (11)41 (8)
  Hispanic50 (12)29 (16)33 (10)24 (8)9 (4)34 (4)
  Others12 (10)3 (9)14 (12)13 (12)4 (7)6 (4)
 Menopause (% women)N/AN/A4 (7)6 (10)0.5426 (60)84 (78)0.08
 BMI (kg/m2) 0.79 0.004 0.44
 BMI -score 0.33N/AN/A
 Triglycerides (mg/dL) <0.0001 <0.0001 <0.0001
 HDL C (mg/dL) <0.0001 <0.0001 <0.0001
 Systolic BP (mmHg) 0.007 0.0003 <0.0001
 Diastolic BP (mmHg) 0.5 <0.0001 0.51
 Fasting glucose (mg/dL) 0.002 <0.0001 <0.0001

Mean ± SE or (%).
Obesity among adolescents defined by age/sex-specific BMI >95% percentile [31]; obesity among adults defined by BMI ≥30.0 kg/m2; MHO: 0, 1 abnormal cardiometabolic risk factor; MUO: ≥2 abnormal cardiometabolic risk factors.
Log transformed for t-test analysis.
NA: not applicable.