The Intrauterine and Nursing Period Is a Window of Susceptibility for Development of Obesity and Intestinal Tumorigenesis by a High Fat Diet in Min/+ Mice as Adults

Figure 2

The feed intake of the dams during (a) pregnancy, that is, from mating to the end of week 3 of pregnancy (), and (b) the three week lactation period (), recorded as gram diet per gram body weight per week (mean ± SD). During pregnancy, the dams were given either a 10% fat (white columns) or a 45% fat diet (black columns). The data for the lactation period were stratified according to the four different combinations of the 10% fat or 45% fat diet during pregnancy and the 10% fat or 45% fat diets during the lactation period; 10+10+ (white columns), 45+10+ (light grey columns), 10+45+ (dark grey columns), 45+45+ (black columns), as explained in the legend to Figure 1. (a) ignificantly higher with a 10% fat diet versus a 45% fat diet within the same week. (b) ignificantly higher with a 10% fat diet during both pregnancy and nursing periods versus a 45% fat diet in the same periods within the same week. (b) ignificantly higher with a 45% fat diet during pregnancy and a 10% fat diet during nursing versus a 45% fat diet in both periods within the same week.

(a)

(b)