Research Article

Unhealthy Phenotype as Indicated by Salivary Biomarkers: Glucose, Insulin, VEGF-A, and IL-12p70 in Obese Kuwaiti Adolescents

Table 1

Demographic data and clinical characteristics of 8,317 enrolled children overall and by weight category.

Body weight categoryOverall
UnderweightNormal weightOverweightObese

(%)193 (2.3)4,129 (49.6)1,791 (21.5)2,204 (26.5)8,317 (100)
Age (y)9.8 0.69.9 0.710.0 0.710.1 0.710.0 0.7
Waist circumference (cm)54.3 5.160.4 10.170.2 7.184.1 28.368.7 19.4
BMI (kg/m2)13.5 0.817.1 1.621.7 1.327.9 4.320.9 5.3
Salivary glucose concentration (mg/dL)0.20 0.250.20 0.250.18 0.220.20 0.260.19 0.24
Salivary glucose ≥ 1.13 mg/dL, (%)4 (2.1)72 (1.7)27 (1.5)38 (1.7)141 (1.7)
Saliva flow rate (mL/h)22.8 12.424.9 14.526.8 15.727.8 17.226.0 15.6
Diastolic blood pressure (mm Hg)69.2 12.470.2 16.275.5 19.381.3 27.074.3 20.7
Systolic blood pressure (mm Hg)101.1 13.9103.3 14.8112.3 14.4119.4 14.8109.4 16.3
Hypertension, (%)26 (13.5)574 (13.9)426 (23.8)964 (43.8)1990 (23.9)

All significantly different except for “underweight” and “normal weight” ().
All categories significantly different ).
All categories significantly different except for “overweight” compared to “obese” ().