Journal of Obesity

Research Article

Prevalence of GCKR rs1260326 Variant in Subjects with Obesity Associated NAFLD and T2DM: A Case-Control Study in South Punjab, Pakistan

Table 3

Genotype and allelic frequencies of GCKR rs1260326 in obese NAFLD vs control.
Genotypes (n = total)CC, n(%)CT, n(%)TT, n(%)C allele frequency, n(%), fT allele frequency, n(%), f
NW (n = 34)18 (52.94%)9 (26.47%)7 (20.58%)45 (66.18%), 0.6623 (33.82%), 0.34
OW (n = 38)19 (50%)13 (34.21%)6 (15.78%)51 (67.11%), 0.6725 (32.89%), 0.33
OB (n = 31)18 (58.06%)10 (32.25%)3 (9.67%)46 (74.19%), 0.7416 (25.81%), 0.26
HS (n = 50)9 (18%)34 (68%)7 (14%)52 (52%), 0.5248 (48%), 0.48
NW: normal weight (BMI >18.5 to <25), OW: overweight (BMI 25 to<30), OB: obese (BMI >30, CC: mutant type, CT: heterotype, TT: wild type. Allelic frequencies of genotypes were calculated according to Hardy–Weinberg equation.