Journal of Obesity

Research Article

Prevalence of GCKR rs1260326 Variant in Subjects with Obesity Associated NAFLD and T2DM: A Case-Control Study in South Punjab, Pakistan

Table 4

Genotype and allelic frequencies of GCKR rs1260326 in obese T2DM vs control.
Genotypes (n = total)CC, n(%)CT, n(%)TT, n(%)C allele frequency, n(%), fT allele frequency, n(%), f
NW (n = 30)15 (50%)9 (30%)6 (20%)36 (60%), 0.6024 (40%), 0.40
OW (n = 43)20 (46.51%)11 (25.58%)12 (27.90%)52 (60.47%), 0.6034 (39.53%), 0.40
OB (n = 27)18 (66.66%)5 (18.51%)4 (14.81%)40 (74.07%), 0.7414 (25.93%), 0.26
HS (n = 50)11(22%)29 (58%)10 (20%)68 (32%), 0.3232 (68%), 0.68
NW: normal weight (BMI >18.5 to <25), OW: overweight (BMI 25 to <30), OB: obese (BMI >30, CC: mutant type, CT: heterotype, TT: wild type. Allelic frequencies of genotypes were calculated according to Hardy–Weinberg equation.