Research Article

Prevalence of GCKR rs1260326 Variant in Subjects with Obesity Associated NAFLD and T2DM: A Case-Control Study in South Punjab, Pakistan

Table 5

Genotype and allelic frequencies of GCKR in NAFLD and T2DM subjects.

Genotypes (n= total)CC, n(%)CT, n(%)TT, n(%)C allele frequency, n(%), fT allele frequency, n(%), f

NAFLD (n = 103)55 (53.39%)16 (15.53%)32 (31.06%)142 (68.93%), 0.689364 (31.06%), 0.3107
T2DM (n = 100)53 (53%)22 (22%)25 (25%)131 (65.5%), 0.65569 (34.5%), 0.345

NW: normal weight (BMI >18.5 to <25), OW: overweight (BMI 25 to <30), OB: obese (BMI >30, CC: mutant type, CT: heterotype, TT: wild type. Allelic frequencies of genotypes were calculated according to Hardy–Weinberg equation.