The Concentrations of Interleukin-6, Insulin, and Glucagon in the Context of Obesity and Type 2 Diabetes and Single Nucleotide Polymorphisms in IL6 and INS Genes

Table 8

Relationship between the selected parameters and the risk of developing obesity.

SNP (gene)	Genotype	Obese group	Control group		OR	95% CI OR
rs1800795 (IL6)	G/G	17	18	0.379	1.667	0.535–5.196
	G/C	26	18	0.094	2.556	0.853–7.655
	C/C	14	14	—	1.000	—
rs3842729 (INS)	A/G	32	23	—	1.000	—
	G/G	25	27	0.073	0.470	0.206–1.073
Other variables	Category	Obese group	Control group		OR	95% CI OR
Age (years)	—	—	—	<0.000	1.087	1.045–1.131
Sex	Men	27	21	—	1.000	—
	Women	30	29	0.270	0.634	0.281–1.426
Smoking status	Yes	19	7	0.010	3.730	1.371–10.145
	No	38	43	—	1.000	—

Data were obtained with the logistic regression analysis. OR: odds ratio; CI: confidence interval; statistical significance: Values that are statistically significant are in bold.