The Concentrations of Interleukin-6, Insulin, and Glucagon in the Context of Obesity and Type 2 Diabetes and Single Nucleotide Polymorphisms in IL6 and INS Genes

Table 9

Relationship between the selected parameters and the risk of developing type 2 diabetes.

SNP (gene)	Genotype	Diabetic group	Control group		OR	95% CI OR
rs1800795 (IL6)	G/G	3	18	0.037	0.212	0.049–0.909
	G/C	9	18	0.431	0.636	0.207–1.959
	C/C	11	14	—	1.000	—
rs3842729 (INS)	A/G	9	23	—	1.000	—
	G/G	14	27	0.583	1.325	0.485–3.621
Other variables	Category	Diabetic group	Control group		OR	95% CI OR
BMI	—	—	—	<0.000	1.672	1.305–2.143
Sex	Men	6	21	—	1.000	—
	Women	17	29	0.195	2.052	0.692–6.084
Smoking status	Yes	3	7	0.912	0.921	0.216–3.939
	No	20	43	—	1.000	—

Data were obtained with the logistic regression analysis. OR: odds ratio; CI: confidence interval; statistical significance: . Values that are statistically significant are in bold.