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Cellular Signaling Mediated by Physical Activity or Bioactive Compounds

Call for Papers

Driven by the marked obesity epidemic, interest in understanding the complex genetic and environmental basis of body weight and composition is great. It has led the scientific community to investigate the physiological basis of energy homeostasis and mechanisms of satiety. On one hand, obesity is a disease currently considered out of control, where bariatric surgeries or drugs therapy has not been enough to maintain the control over obesity; on the other hand, there are some important strategies for weight loss which include dietary, exercise, and behavioral modification. Substantial progress has been made concerning our knowledge of bioactive components, acute or chronic exercise programs, and their links to health (articles with identification and analysis of haplotype-nutrient or physical activity interactions are encouraged).

The future study of nutrigenomics and physiogenomics offers the opportunity to clarify the underlying molecular mechanisms governing the interactions between dietary, exercise, and the obesity phenotype. Thus, we invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the molecular mechanisms and that explore aspects of the nutrigenomics and physiogenomics applied in obesity in humans and in animal models. Potential topics include, but are not limited to:

  • Pro- and anti-inflammatory control
  • Reticulum stress and autophagia signaling
  • Oxidative stress and pro- and antiapoptotic pathways
  • Polymorphism and mutations controlled by exercise and nutrition
  • Epigenetics control
  • Metaflammation
  • The impact of nutrition and exercise on cardiometabolic risk

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/jobe/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/jobe/cels/ according to the following timetable:

Manuscript DueFriday, 3 January 2014
First Round of ReviewsFriday, 28 March 2014
Publication DateFriday, 23 May 2014

Lead Guest Editor

  • Claudio Teodoro De Souza, Laboratory of Exercise Biochemistry and Physiology, Health Sciences Unit, Universidade do Extremo Sul Catarinense, Avenida Universitária, Criciuma, SC, Brazil

Guest Editors

  • Fabio Santos Lira, Immunometabolism Research Group, Department of Physical Education, São Paulo State University, São Paulo, SP, Brazil
  • José Rodrigo Pauli, Laboratory of Molecular Biology of Exercise, State University of Campinas, Campinas, SP, Brazil
  • Eduardo Rochete Ropelle, Laboratory of Molecular Biology of Exercise, State University of Campinas, Campinas, SP, Brazil
  • Dennys Esper Cintra, Laboratory of Nutritional Genomics–Nutrigenomics and Lipids Center, State University of Campinas, Campinas, SP, Brazil
  • Atul Deshmukh, Department of Proteomics and Signal Transduction, Max Planck Institute for Biochemistry, Martinsried, Munich, Germany