Table 1: Weight gain treatment options.

Mode or medication Weight loss produced Duration of treatment Behaviour modification 0.5–0.7 kg per week — Cognitive-behavioral therapy 4.5 drop in BMI — Naltreoxone and buropion 4% — Phentermine and topiramate 9% 1 year Sibutramine 10–15% <1 year Orlistat 10.2%, 8.8% 1 year Orlistat >10% 2 years Orlistat 34.6% ? Amantadine 3.5 kg 3–6 months Nizatidine Gained 3 kg less than patients who did not take Nizatidine 16 weeks Naltexone 5 kg 8 weeks Topiramate augmentation 10–15 lbs — Metformin 15/19 patients lost weight 12 weeks