Table 4: Relative transcript abundances of inflammatory and metabolic markers in subcutaneous adipose tissue before and after diet intervention for all subjects.
Gene
Baseline
Endpoint
TNF-α
100.0 ± 8.3
97.1 ± 7.3
IL-6
100.0 ± 11.1
150.9 ± 23.1*
MCP-1
100.0 ± 10.5
105.2 ± 8.5
CD68
100.0 ± 5.3
116.5 ± 8.2
CD11b
100.0 ± 10.0
117.3 ± 12.0
CD11c
100.0 ± 9.1
105.4 ± 8.5
CD11d
100.0 ± 6.2
133.2 ± 9.6**
IL-1β
100.0 ± 14.1
114.8 ± 11.7
IL-10
100.0 ± 7.7
118.4 ± 8.1
IL-15
100.0 ± 6.1
103.4 ± 6.0
FAS
100.0 ± 12.6
114.9 ± 14.4
UCP2
100.0 ± 4.4
110.3 ± 6.1
Values are expressed as % of baseline average level (mean + SEM). * and ** compared to baseline, paired -test. TNF: tumor necrosis factor; IL: interleukin; MCP: monocyte chemoattractant protein; FAS: fatty acid synthase; UCP: uncoupling protein. .