Journal of Oral Diseases http://www.hindawi.com The latest articles from Hindawi Publishing Corporation © 2014 , Hindawi Publishing Corporation . All rights reserved. Variable Selection Method in Prediction Models: Application in Periodontology Tue, 04 Feb 2014 13:30:51 +0000 http://www.hindawi.com/journals/jod/2014/823530/ The aim of this study, applied in the field of periodontal diseases, was first to analyze the fatty acid levels in two groups of patients and then to propose a method for selecting the most relevant predictors. Two groups of patients, 29 with moderate or severe periodontitis and 27 who served as controls, were clinically examined, and their fatty acids in serum were measured by gas chromatography. The levels of these 12 fatty acids were the variables of the analysis. Logistic regression, together with the area under the receiver operating characteristic (ROC) curves, allowed determining a composite score which led to a subset of the most relevant covariables. The fatty acid levels differed significantly between the 2 groups in multivariate analysis () and the best logistic model was obtained with only 3 predictive variables: arachidonic acid, linoleic acid, and DHA. Fatty acid levels in serum of patients were significantly different according to the presence of moderate or severe periodontitis. By taking into account the comparison of ROC curves, our approach could optimize the choice of variables in multivariate analyses and could better fit it with diagnosis and prognosis of oral diseases in dental research. Paul Tramini, Jean-Christophe Chazel, Isabelle Calas-Bennasar, Philippe Gibert, and Nicolas Molinari Copyright © 2014 Paul Tramini et al. All rights reserved. Talon Cusp: A Prevalence Study of Its Types in Permanent Dentition and Report of a Rare Case of Its Association with Fusion in Mandibular Incisor Tue, 21 Jan 2014 09:14:51 +0000 http://www.hindawi.com/journals/jod/2014/595189/ Purpose. The data on various types of talon cusp, a rare developmental anomaly that occurs predominantly on palatal surfaces of maxillary incisors with varied prevalence in different populations, is scarce. Thus, the purpose of study was to evaluate prevalence of various types of talon cusp and its association with sex predilection, site, and other dental anomalies and complications. Subjects and Methods. A cross-sectional prevalence study for various types of talon cusp was conducted in 5200 patients selected randomly. Hattab’s classification criterion was used for diagnosis of types of talon cusp. The clinical diagnosis was confirmed with radiograph. Results. The prevalence of talon cusp was found to be 0.02% (1 in 430 cases). 12 cases of talon cusp in 10 patients (60% males) were documented (2 bilateral cases and 8 unilateral). Type I talon cusp and type II talon cusp were present in five cases each (40.1%) and type III talon cusp was observed in two (16.2%) cases. Conclusion. Type I talon cusp and type II talon cusp were the most common types and permanent maxillary central incisor was the most commonly involved tooth (50%). An extremely rare case of talon cusp on a fused permanent mandibular incisor is also reported. Gaurav Sharma and Archna Nagpal Copyright © 2014 Gaurav Sharma and Archna Nagpal. All rights reserved. Apoptosis and Its Significance in Oral Diseases: An Update Mon, 30 Dec 2013 08:43:14 +0000 http://www.hindawi.com/journals/jod/2013/401049/ Apoptosis is a well defined mode of cell death which plays an imperative role in the development, regulation, and maintenance of the cell populations in multicellular organisms. Apoptosis is implicated in both health and diseases. Errors in apoptotic mechanisms have been allied to a wide range of pathologies including oral diseases. This review presents an update focused on the role and significance of apoptosis in various oral diseases ranging from reactive to benign and malignant pathologies. Megha Jain, Sowmya Kasetty, Sudheendra Udyavara Sridhara, Nitin Jain, Samar Khan, and Ami Desai Copyright © 2013 Megha Jain et al. All rights reserved. Effect of Scaling and Root Planing on Detection of Tannerella forsythia in Chronic Periodontitis Sun, 22 Dec 2013 15:14:58 +0000 http://www.hindawi.com/journals/jod/2013/383746/ Aim. This study was aimed to determine the prevalence of Tannerella forsythia in subgingival plaque samples of chronic periodontitis patients having different level of periodontal destruction and to assess the effect of scaling and root planing (SRP) on prevalence of T. forsythia. Materials and Methods. Study included 3 groups: group 1 were healthy individuals, group 2 had periodontitis with probing depth ≤ 5 mm, and group 3 had periodontitis with probing depth > 5 mm. Subjects in groups 2 and 3 exhibited both healthy and diseased periodontal sites. Prevalence of T. forsythia was determined using polymerase chain reaction. Subjects in groups 2 and 3 received SRP and were reevaluated three months after SRP. Results. T. forsythia was not detected in group 1. It was found in diseased sites in 40% and 73.33% of patients from groups 2 and 3, respectively. It was also found in healthy sites in 6.67% and 13.33% of patients from groups 2 and 3, respectively. The detection frequency of T. forsythia after SRP was 6.67% and 13.33% in groups 2 and 3, respectively. Conclusion. The results indicate a possible association between periodontal disease and presence of T. forsythia. Also, the detection frequency of T. forsythia was reduced after SRP. Ritesh B. Wadhwani, Minal S. Chaudhary, Dipti A. Tharani, and Shweta A. Chandak Copyright © 2013 Ritesh B. Wadhwani et al. All rights reserved. Clinically Classified Periodontitis and Its Association in Patients with Preexisting Coronary Heart Disease Wed, 19 Jun 2013 13:04:05 +0000 http://www.hindawi.com/journals/jod/2013/243736/ The aim of this retrospective study was to investigate possible associations between clinically classified periodontitis as determined by assessing its severity and diagnosed coronary heart disease in outpatients referred to a specialist clinic for neurosurgery treatment. A total of 2,912 individuals were clinically examined for periodontal disease experience by using probing pocket depth (PPD) and clinical attachment loss (CAL). Socioeconomic, oral health behaviour, and general health related information was collected by using a self-administered questionnaire. Statistical analysis of the questionnaire items was performed by using multivariate logistic regression analysis model. The results showed that the occurrence of hypertension (, 95% CI = 1.52–3.84), smoking (, 95% CI = 1.25–3.11), classified periodontitis (, 95% CI = 1.15–2.77), and the high level of serum C-reactive protein (, 95% CI = 1.05–2.89) were significantly associated with the presence of coronary heart disease. These observations strengthen the role of some of the traditional causative risk factors for coronary heart disease while a significant association was recorded between diagnosed coronary heart disease and clinically classified periodontitis which is considered as a risk factor for coronary heart disease. Nikolaos A. Chrysanthakopoulos and Panagiotis A. Chrysanthakopoulos Copyright © 2013 Nikolaos A. Chrysanthakopoulos and Panagiotis A. Chrysanthakopoulos. All rights reserved.