Clinical Study

Head and Neck Solitary Extramedullary Plasmacytoma

Table 3

Comparison of the results of patients with extramedullary solitary plasmacytoma of the head and neck in Aliexiou’s et al.’s literature review [31] with the present study [6, 9, 1422, 27, 28, 30, 31].

VariablesAlexiou’s LR (before 1998) [31]Present LR (1998–2012)aPresent studyOverall

Patients’ number714345131072
Primary sites
 Sinonasal tract313 (44%)163 (47%)9 (69%)485 (45%)
 Nasopharynx131 (18%)51 (15%)1 (8%)183 (17%)
 Oral cavity22 (3%)35 (10%)0 (0.0%)57 (6%)
 Oropharynx103 (15%)26 (7.5%)0 (0.0%)129 (12%)
 Larynx79 (11%)26 (7.5%)0 (0.0%)105 (10%)
 Hypopharynx4 (0.5%)2 (0.5%)0 (0.0%)6 (0.5%)
 Salivary glands29 (4%)4 (1%)0 (0.0%)33 (3%)
 Cervical L.N.12 (1.5%)13 (4%)2 (15%)27 (2.5%)
 Orbit0 (0.0%)13 (4%)0 (0.0%)13 (2%)
 Miscellaneous16 (2%)12 (3.5%)1 (8%)29 (3%)
Local control rate78%87%89%81%
Progression to MM rate16.1%21%15%17.7%
5-year OS73.3%72.5%74.1%73%
10-year OS68.5%69%74.1%69%

LR: literature review; L.N.: lymph node; MM: multiple myeloma; OS: overall survival.
a[6, 9, 1422, 27, 28, 30, 31].