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Journal of Ophthalmology
Volume 2010 (2010), Article ID 861291, 9 pages
doi:10.1155/2010/861291
Identification of Diabetic Retinopathy Genes through a Genome-Wide Association Study among Mexican-Americans from Starr County, Texas
1Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, P.O. Box 20186, Houston, TX 77225, USA
2Valley Retina Institute, McAllen, TX 78503, USA
3Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA
4Division of Endocrinology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
5Department of Human Genetics, The University of Chicago, Chicago, IL 60637, USA
Received 18 December 2009; Revised 22 May 2010; Accepted 14 July 2010
Academic Editor: Kavita Hegde
Copyright © 2010 Yi-Ping Fu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Supplementary Material
Supplementary materials contains:
Supplementary Figure 1. Q-Q plot of logistic regression models adjusted for age, gender, diabetes duration and HbA1C level.
Supplementary Figure 2. Q-Q plot of SNPs located in coding region of 208 diabetic retinopathy candidate genes.
Supplementary Table 1. Detail information of SNPs with pvalues of Fisher's Exact allelic test less than 0.05.
Supplementary Table 2. Imputation quality of SNP markers used in MACH.
Supplementary Table 3. A list of 208 retinopathy candidate genes has been generated.