Table 2: (a) 10-year incidence of dry eye in older population—relative risk due to medication (Beaver Dam Study [10]). (b) Association of dry eye in older population due to medication [11]**, [12]*.

(a)

Drug Relative risk P value Antihistamine use 1.24 0.05 Antianxiety drug use 1.43 0.02 Antidepressant use 1.44 0.03 Diuretic use 1.18 0.06 Oral steroid use 1.43 0.01 Vitamin use 1.30 0.02

(b)

Drug Odds ratio 95% confidence interval Antiandrogen* 1.35 1.01–1.80 Antidepressants* 1.90 1.39–2.61 Aspirin**      (1/day) 1.07 0.69–1.67  (≥2/day) 1.98 1.36–2.89