Table 4: Topical ocular drugs that may cause or aggravate dry eye [13].

Class Examples Agents used to treat glaucoma    Beta-blocking agents Betaxolol Carteolol Levobunolol Metipranolol Timolol  Adrenergic agonist  drugs Apraclonidine Brimonidine  Carbonic anhydrase  inhibitors Brinzolamide Dorzolamide  Cholinergic agents Pilocarpine  Prostaglandins Bimatoprost Latanoprost Travoprost Dipivefrine Unoprostone Ecothiopate Agents used to treat allergies Emedastine Olopatadine Antiviral agents Aciclovir Idoxuridine Trifluridine Decongestants Naphazoline Tetryzoline Miotics Dapiprazole Mydriatics and cycloplegics Cyclopentolate Tropicamide Hydroxyamfetamine Preservatives Benzalkonium chloride Topical local anesthetics Cocaine Proxymetacaine Tetracaine Topical ocular NSAIDs Bromfenac Diclofenac Ketorolac Nepafenac