Anti-VEGF Treatment Strategies for Wet AMD

Figure 2

(a) A binding domain of VEGFR1 and VEGFR2 are fused to create 2 dual-domain arms for each VEGF Trap-Eye molecule. (b) The Fc portion of the IgG is fused to the two dual-domain arms to create the VEGF Trap-Eye molecule (see [9]).

(a)

(b)