Inhibition of Methylglyoxal-Mediated Protein Modification in Glyoxalase I Overexpressing Mouse Lenses

Figure 1

Human Glo I minigene construct. The human Glo I gene was linked to the chimeric promoter that contains the mouse $\alpha$A-crystallin promoter ($\alpha$A-P) and chick $\delta$1-crystallin lens enhancer ($\delta$ -en), which drives the expression of Glo I specifically in the lens epithelium and fiber cells.