AKR1B10 expression in the transgenic lens. (a) Western blot demonstrating expression of AKR1B10 in lens of transgenic (Tg) mice; the characteristic band was not observed in lenses from nontransgenic (NTg) controls. Aldo-keto reductase enzyme activity in lenses is shown below each lane. (b) and (c) Immunohistochemical stain for AKR1B10 expression in the transgenic lens.
