Table 1: Ocular pathological findings in diabetic human, SDT rats, and STZ-induced diabetic rats.

HumanSDT ratsSTZ rats

Retina
 HyperpermeabilityYesYesYes
 Retinal detachmentYesYesNo
 Retinal thicknessYesYesYes
 Avascular areaYesNoNo
 NeovascularizationYesYesYes
 Retinal microaneurysmYesNoNo
 Pericyte lossYesYesYes
 Vessel abnormalityYesYesYes
 VEGF expressionHighHighHigh
 PEDF expressionLowHighHigh
Vitreous body
 Proliferative membraneYesYesNo
Iris
 NeovascularizationYesYesNo
Lens
 CataractYesYesYes
(senile cataract true diabetic cataract)(true diabetic cataract)(true diabetic cataract)