About this Journal Submit a Manuscript Table of Contents
Journal of Ophthalmology
Volume 2010 (2010), Article ID 746978, 10 pages
http://dx.doi.org/10.1155/2010/746978
Research Article

NADPH Oxidase versus Mitochondria-Derived ROS in Glucose-Induced Apoptosis of Pericytes in Early Diabetic Retinopathy

1Forest Research Institute Malaysia (FRIM), 52109 Kepong, Selangor Darul Ehsan, Malaysia
2Cardiovascular Division, GKT School of Biomedical & Health Sciences, King's College London, Guy's Campus, London SE1 1UL, UK
3Institute of Biomedical and Clinical Science, Peninsula College of Medicine and Dentistry, Peninsula Medical School, St Luke's Campus, Exeter EX1 2LU, UK

Received 1 January 2010; Revised 29 March 2010; Accepted 23 April 2010

Academic Editor: Renu A. Kowluru

Copyright © 2010 Nik M. Mustapha et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [16 citations]

The following is the list of published articles that have cited the current article.

  • Samuel Quimby, and Robert Fern, “Novel morphological features of developing white matter pericytes and rapid scavenging of reactive oxygen species in the neighbouring endothelia,” Journal Of Anatomy, vol. 219, no. 1, pp. 65–77, 2011. View at PublisherView at Google Scholar
  • Fatiha Tabet, Gilles Lambert, Luisa F. Cuesta Torres, Liming Hou, Irene Sotirchos, Rhian M. Touyz, Alicia J. Jenkins, Philip J. Barter, and Kerry-Anne Rye, “Lipid-Free Apolipoprotein A-I and Discoidal Reconstituted High-Density Lipoproteins Differentially Inhibit Glucose-Induced Oxidative Stress in Human Macrophages,” Arteriosclerosis Thrombosis And Vascular Biology, vol. 31, no. 5, pp. 1192–U644, 2011. View at PublisherView at Google Scholar
  • Satish K. Srivastava, Umesh C.S. Yadav, Aramati B.M. Reddy, Ashish Saxena, Ravinder Tammali, Mohammad Shoeb, Naseem H. Ansari, Aruni Bhatnagar, Mark J. Petrash, Sanjay Srivastava, and Kota V. Ramana, “Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders,” Chemico-Biological Interactions, vol. 191, no. 1-3, pp. 330–338, 2011. View at PublisherView at Google Scholar
  • V. Cifarelli, X. Geng, A. Styche, R. Lakomy, M. Trucco, and P. Luppi, “C-peptide reduces high-glucose-induced apoptosis of endothelial cells and decreases NAD(P)H-oxidase reactive oxygen species generation in human aortic endothelial cells,” Diabetologia, vol. 54, no. 10, pp. 2702–2712, 2011. View at PublisherView at Google Scholar
  • Radhika Kapoor, and Poonam Kakkar, “Protective Role of Morin, a Flavonoid, against High Glucose Induced Oxidative Stress Mediated Apoptosis in Primary Rat Hepatocytes,” Plos One, vol. 7, no. 8, 2012. View at PublisherView at Google Scholar
  • Sergey Lupachyk, Roman Stavniichuk, Julia I. Komissarenko, Viktor R. Drel, Alexander A. Obrosov, Azza B. El-Remessy, Pal Pacher, and Irina G. Obrosova, “Na+/H+-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis,” International Journal Of Molecular Medicine, vol. 29, no. 6, pp. 989–998, 2012. View at PublisherView at Google Scholar
  • Qin Shen, Jim Wu, and Jason C. Wong, “Potential drug interventions for diabetic retinopathy,” Drug Discovery Today, 2013. View at PublisherView at Google Scholar
  • Shing Hwa Liu, Wayne Huey Herng Sheu, Maw Rong Lee, Wen Jane Lee, Yu Chiao Yi, Tzung Jie Yang, Jen Fon Jen, Hung Chuan Pan, Chin Chang Shen, Wen Bao Chen, Hsing Ru Tien, and Meei Ling Sheu, “Advanced glycation end product N epsilon-carboxymethyllysine induces endothelial cell injury: the involvement of SHP-1-regulated VEGFR-2 dephosphorylation,” Journal Of Pathology, vol. 230, no. 2, pp. 215–227, 2013. View at PublisherView at Google Scholar
  • R. Dornetshuber-Fleiss, P. Heffeter, T. Mohr, P. Hazemi, K. Kryeziu, C. Seger, W. Berger, and R. Lemmens-Gruber, “Destruxins: Fungal-derived Cyclohexadepsipeptides with Multifaceted Anticancer and Antiangiogenic Activities,” Biochemical Pharmacology, 2013. View at PublisherView at Google Scholar
  • Jennifer L. Wilkinson-Berka, Indrajeetsinh Rana, Roksana Armani, and Alex Agrotis, “Reactive oxygen species, Nox and angiotensin II in angiogenesis: implications for retinopathy,” Clinical Science, vol. 124, no. 9-10, pp. 597–615, 2013. View at PublisherView at Google Scholar
  • Timo Kahles, and Ralf P. Brandes, “Which NADPH Oxidase Isoform Is Relevant for Ischemic Stroke? The Case for Nox 2,” Antioxidants & Redox Signaling, vol. 18, no. 12, pp. 1400–1417, 2013. View at PublisherView at Google Scholar
  • Subhadip Choudhuri, Deep Dutta, Imran H. Chowdhury, Bhaskar Mitra, Aditi Sen, Lakshmi K. Mandal, Satinath Mukhopadhyay, and Basudev Bhattacharya, “Association of hyperglycemia mediated increased advanced glycation and erythrocyte antioxidant enzyme activity in different stages of diabetic retinopathy,” Diabetes Research and Clinical Practice, 2013. View at PublisherView at Google Scholar
  • Ji Chen, Xiang Xiao, Shuzhen Chen, Cheng Zhang, Jianying Chen, Dan Yi, Vinayak Shenoy, Mohan K. Raizada, Bin Zhao, and Yanfang Chen, “Angiotensin-Converting Enzyme 2 Priming Enhances the Function of Endothelial Progenitor Cells and Their Therapeutic Efficacy,” Hypertension, vol. 61, no. 3, pp. 681–689, 2013. View at PublisherView at Google Scholar
  • Radhika Kapoor, Fatima Rizvi, and Poonam Kakkar, “Naringenin prevents high glucose-induced mitochondria-mediated apoptosis involving AIF, Endo-G and caspases,” Apoptosis, vol. 18, no. 1, pp. 9–27, 2013. View at PublisherView at Google Scholar
  • E S Shin, Q Huang, Z Gurel, T L Palenski, I Zaitoun, C M Sorenson, and N Sheibani, “STAT1-mediated Bim expression promotes the apoptosis of retinal pericytes under high glucose conditions,” Cell Death and Disease, vol. 5, no. 1, pp. e986, 2014. View at PublisherView at Google Scholar
  • Britta Fischer, Petra Heffeter, Kushtrim Kryeziu, Lars Gille, Samuel M. Meier, Walter Berger, Christian R. Kowol, and Bernhard K. Keppler, “Poly(lactic acid) nanoparticles of the lead anticancer ruthenium compound KP1019 and its surfactant-mediated activation,” Dalton Transactions, vol. 43, no. 3, pp. 1096, 2014. View at PublisherView at Google Scholar