Clinical Study
Evaluation of Hemodynamic Parameters as Predictors of Glaucoma Progression
Table 4
Comparison of means between progressing and stable glaucoma patients at 18 months visit.
| | Parameter at 18 month | Mean in stable glaucoma patients (St. deviation) | Mean in progressing glaucoma patients (St. deviation) | value
(t-test) |
| | IOP | 15.32 (2.46) | 16.73 (3.04) | .171 | | IOP/POBF | 14.73 (3.5) | 16.88 (3.89) | .123 |
| | MD (dB) | −1.06 (2.30) | −2.01 (2.13) | .257 | | PSD (dB) | 2.05 (2.53) | 2.90 (2.41) | .360 |
| | TSNIT (μ) | 53.59 (5.28) | 50.96 (7.10) | .254 | | NFI | 23.82 (2.36) | 27.69 (3.29) | .0008* |
| | SBP (mmHg) | 151.50 (14.04) | 147.73 (20.66) | .55 | | DBP (mmHg) | 88.44 (6.42) | 83.53 (8.23) | .077 | | OPP (mmHg) | 57.19 (4.73) | 51.84 (7.00) | .019* | | DPP (mmHg) | 73.06 (6.57) | 64.85 (8.82) | .007* |
| | OA_PSV | 32.26 (3.15) | 29.82 (3.28) | .048 | | OA_EDV | 9.19 (4.98) | 7.25 (2.01) | .197 | | OA_RI | 0.74 (0.07) | 0.90 (0.07) | <.0001* |
| | CRA_PSV | 19.96 (7.36) | 15.61 (6.28) | .099 | | CRA_EDV | 6.66 (3.19) | 5.73 (2.85) | .415 | | CRA_RI | 0.79 (0.08) | 0.815 (0.06) | .35 |
| | SPCA_PSV | 13.08 (5.11) | 11.42 (3.43) | .321 | | SPCA_EDV | 4.73 (1.71) | 3.34 (0.83) | .011* | | SPCA_RI | 0.77 (0.20) | 0.76 (0.20) | .893 |
| | AMPLITUDE | 4.62 (1.48) | 4.62 (1.44) | .985 | | PULSE VOLUME | 9.71 (2.01) | 7.03 (1.00) | .0001* | | POBF | 21.25 (4.22) | 19.60 (4.60) | .316 |
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DTFC: dorzolamide/timolol fixed combination; LTFC: latanoprost/timolol fixed combination; MD: mean deviation; PSD: pattern standard deviation; TSNIT: temporal, superior, nasal, inferior, temporal average; NFI: nerve fiber index. POBF: pulsatile ocular blood flow.
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