Research Article

Mouse Model Resources for Vision Research

Table 3

Mouse mutants from the Translational Vision Research Models (TVRMs) program in which the molecular basis of the disease phenotype has not yet been identified.

ModelModeChr.Clinical Phenotype

tvrm9AR1Retinal spots
tvrm113AR4Retinal spots, grainy fundus appearance
Tvrm6 AD7Retinal spots
tvrm116AR12Retinal spots, late onset
tvrm111AR14Retinal spots
nmf289AR16Retinal spots
tvrm5AR18Retinal spots in central retina
tvrm10AR19Retinal spots, coloboma, and vascular defects
tvrm77AR6Central patches
tvrm119AR18Retinal patches
tvrm127AR18Retinal patches
tvrm102AR6Grainy retina
tvrm101AR10Grainy retina
nmf67AR7Fine web-like fundus appearance
Tvrm122AD3Shiny flecks
tvrm64aAR12None, identified through histology, lamination defect
tvrm111bAR8Abnormal ERG
tvrm87AR4Vitreal fibroplasia
tvrm114AR4Vitreal fibroplasia, cataracts
tvrm53AR7Vitreal fibroplasia
tvrm85AR18Vitreal fibroplasia
Tvrm49AD15Cataracts
tvrm129AR13Cataracts