Contribution of Cholesterol and Oxysterols in the Physiopathology of Cataract: Implication for the Development of Pharmacological Treatments
Figure 1
Cholesterol autoxidation. Autoxidation of cholesterol can generate 7α- or 7β-hydroperoxyde, 7α- or 7β-hydroxycholesterol, 7-ketocholesterol, 5α, 6α- or 5β, 6β-epoxycholesterol, as well as cholesterol 3β, 5α, 6β triol or cholesterol 3β, 5α, 6α triol depending on pH conditions.