Cellular Origin of Spontaneous Ganglion Cell Spike Activity in Animal Models of Retinitis Pigmentosa
Figure 1
Spontaneous activity in rd1 alpha ganglion cell. (a) Whole-cell current clamp recordings of ongoing spiking activity in wild-type (top) and rd1 (bottom) ON-type retinal ganglion cells. Horizontal tick mark at left indicates −60 mV for wt and −70 mV for rd1 cells, respectively. (b) Whole-cell voltage clamp recording of ongoing synaptic currents in an rd1 ON ganglion cell before (left) and after (right) bath application of CNQX.
