Retrobulbar Hemodynamic Effects of Nipradilol in Normal and Normal-Tension Glaucoma Eyes

Table 3

Systemic and ocular parameters before and after topical application of nipradilol in normal-tension glaucoma.

Parameter	Before	2 hrs (𝑃)	4 weeks (𝑃)
Intraocular pressure (mmHg)	15.3 ± 2.2	13.7 ± 2.2 (0.0004)*	14.0 ± 1.3 (0.0052)*
Blood pressure
Systolic (mmHg)	130.0 ± 19.2	131.0 ± 21.7 (0.6456)	129.0 ± 19.8 (0.7206)
Diastolic (mmHg)	78.7 ± 13.4	81.2 ± 11.8 (0.1363)	77.7 ± 11.6 (0.5139)
Heart rate (beats/min)	71.4 ± 11.9	65.7 ± 11.7 (0.0067)*	68.1 ± 13.6 (0.3316)
Ocular perfusion pressure (mmHg)	48.6 ± 9.2	51.5 ± 8.8 (0.0002)*	49.2 ± 8.8 (0.4443)

Wilcoxon signed-rank sum test.
Values are presented as mean ± standard deviation.
(𝑃)^∗<0.05.