Retrobulbar Hemodynamic Effects of Nipradilol in Normal and Normal-Tension Glaucoma Eyes
Table 4
Results of color Doppler imaging in normal tension glaucoma with topical nipradilol.
Parameter
Before
2 hrs ( value)
4 week ( value)
Ophthalmic artery
PSV (cm/sec)
28.4 ± 10.8
24.7 ± 9.3 (0.0028)*
26.0 ± 9.0 (0.0871)
EDV (cm/sec)
7.71 ± 3.73
7.07 ± 3.26 (0.0859)
7.44 ± 3.67 (0.3490)
Resistance index
0.725 ± 0.084
0.712 ± 0.071 (0.4552)
0.721 ± 0.058 (0.7022)
Central retinal artery
PSV (cm/sec)
9.89 ± 3.31
10.9 ± 4.4 (0.0198)*
10.3 ± 4.0 (0.3317)
EDV (cm/sec)
2.88 ± 1.17
3.50 ± 1.43 (0.0003)*
3.25 ± 1.35 (0.0133)*
Resistance index
0.711 ± 0.046
0.676 ± 0.035 (0.0002)*
0.683 ± 0.041 (0.0010)*
NPCA
PSV (cm/sec)
9.03 ± 3.23
9.52 ± 4.31 (0.3134)
7.67 ± 2.43 (0.0365)*
EDV (cm/sec)
3.18 ± 1.40
3.77 ± 1.97 (0.0064)*
2.92 ± 0.94 (0.9108)
Resistance index
0.651 ± 0.061
0.607 ± 0.050 (0.0023)*
0.616 ± 0.052 (0.0124)*
TPCA
PSV (cm/sec)
8.76 ± 2.53
10.2 ± 3.4 (0.0048)*
8.43 ± 2.24 (0.5256)
EDV (cm/sec)
2.95 ± 0.93
4.05 ± 1.43 (0.0001)*
3.25 ± 1.01 (0.1303)
Resistance index
0.662 ± 0.055
0.601 ± 0.048 (0.0007)*
0.615 ± 0.047 (0.0040)*
Values are presented as mean ± standard deviation. PSV: peak systolic velocity, EDV: end-diastolic velocity, NPCA: nasal short posterior ciliary artery, TPCA: temporal short posterior ciliary artery. Wilcoxon signed-rank sum test. .
