The Domestic Cat as a Large Animal Model for Characterization of Disease and Therapeutic Intervention in Hereditary Retinal Blindness
Figure 4
CRX protein structure in Felis catus. Wildtype feline CRX protein (a) compared to the putative truncated CRX protein (b). The exon splice junctions are noted as “Y”. The start codon and stop codons are labeled as (*) and (X), respectively. The protein domains are highlighted as shaded boxes and defined as the homeobox, the WSP domain, the transcriptional transactivation domains 1 and 2 (TTD1 and TTD2), and the OTX tail. Domains are drawn to scale. Reproduced with permission from [26].
