Table 1: Systemic medications that may cause both dry mouth and dry eyes [79].

Class of drugs

Adjuncts to anesthesiaAntipyretic agents
AnalgesicsAntirheumatic agents
AntiandrogensAntispasmodics
AntiarrhythmicsAntivirals
AnticholinergicsAnxiolytics
AntidepressantsBronchodilators
AntiemeticsChelating agents
AntihistaminesDecongestants
AntihypertensivesDiuretics
Antileprosy agentsNeurotoxins
Antimalarial agentsOpioids
AntimuscarinicsPsychedelic agents
AntineoplasticsRetinoids
AntiparkinsoniansSedatives and hypnotics
Antipsychotics