Table 4: Topical ocular drugs that may cause or aggravate dry eye [13].

ClassExamples

Agents used to treat glaucoma
 Beta-blocking agentsBetaxolol
Carteolol
Levobunolol
Metipranolol
Timolol
 Adrenergic agonist  drugsApraclonidine
Brimonidine
 Carbonic anhydrase  inhibitorsBrinzolamide
Dorzolamide
 Cholinergic agentsPilocarpine
 ProstaglandinsBimatoprost
Latanoprost
Travoprost
Dipivefrine
Unoprostone
Ecothiopate

Agents used to treat allergiesEmedastine
Olopatadine

Antiviral agentsAciclovir
Idoxuridine
Trifluridine

DecongestantsNaphazoline
Tetryzoline

MioticsDapiprazole

Mydriatics and cycloplegicsCyclopentolate
Tropicamide
Hydroxyamfetamine

PreservativesBenzalkonium chloride

Topical local anestheticsCocaine
Proxymetacaine
Tetracaine

Topical ocular NSAIDsBromfenac
Diclofenac
Ketorolac
Nepafenac